Frequently asked questions

Is it possible to do full tumor histology, imunohistochemical and gene mutation for brain tumors according to new WHO classification of brain tumors?

From paraffin blocks it is possible to do usual histology, immunohistochemistry (IHC) for IDH1 (according to WHO) and ATRX mutations, and other different IHC markers (Olig2, Synapt, GFAP, Ki67, EMA, STTR2 and others) for differential diagnosis.

Having material unfixed in formalin (fresh or frozen), it would be possible to perform karyotyping (including 1p19q co-deletion for oligodedroglioma, according WHO), testings for IDH1/2, TERT, MGMT mutations.

What are possibilities to examine peripheral nerve biopsies?

Biopsies of peripheral nerves are examined for specific pathology extremely rare, but technical basis of laboratory gives an opportunity to explore nerves by paraffin and resin semi-thin histology using a panel of conventional and immunohistochemical stains or/and electron microscopy.

What rules apply for pathology testing in ophthalmopathology?

No special rules are installed for fixation and histological examination of eyeball, cornea or eyelids. Only cornea routinely is stained additionally by PAS histochemical method in order to better visualize cornea structures.

How to handle skeletal muscle biopsy?

Muscle biopsy (of about 0.5-1 cm) must be put in a dry vial and kept on ice (+4C) and delivered to laboratory before the ice melts (usually in 24 hours).

Common questions that are asked about our services 

Did not find the answer you were looking for? ask@vpc.lt